12/31/2023 0 Comments Types of amnesia brain injury![]() ![]() "Our study doesn't prove exactly what is wrong with them," Siddiqi said. While that might sound like a positive change, Siddiqi said that's not the case. "With people with traditional major depression, these circuits are under-connected, there's less connectivity in the circuits, and after a brain injury, there seems to be increased connectivity of these circuits." "The reason why the different way is important is because it tells us there's a different entity happening, a different disease process," Siddiqi explained. The new imaging technique specifically looked at how oxygen is moving in the brain, providing scientists with detailed maps of the brains of 273 adults with traumatic brain injuries. But by comparing the images, it became clear that the ways in which these circuits operated were different. ![]() The researchers found that brain circuits associated with depression were activated in both people who had the mental health condition with and without a TBI. Specifically, Siddiqi and his colleagues looked at brain scans from people with depression after a TBI, people who had depression without a TBI, and brain scans of people with and without post-traumatic stress disorder. Instead, Siddiqi said experts needed a "biological filter." Thanks to updated imaging technology, he might have found just that, as detailed in the new study. ![]() It turns out that symptom clustering alone is not good enough." "What we had to do was identify clusters of symptoms that go together, and then see if they predict treatment outcomes. "We have believed for a long time that TBI after depression is somehow different, but we have never proven it," Siddiqi said, adding that there are a few reasons why it's been difficult for scientists to definitively demonstrate, such as limited technology. This new study could contribute to changing the way the mental health condition is treated in the future. In the study, researchers propose the new subtype named "TBI affective syndrome." The research adds more evidence to the belief that some psychologists, neurologists and psychiatrists have long held, but have found it difficult to scientifically prove: that there are many subtypes of depression. Siddiqi's latest research, published this month in the journal Science Translational Medicine, suggests that the kind of depression that occurs after a traumatic brain injury is different from other types of depression. "We have believed for a long time that TBI after depression is somehow different, but we have never proven it." ![]()
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